What are the disadvantages of ptfe sterilizing filter membrane?

In drug analysis and dissolution experiments, filter membrane adsorption is the most common drawback of using microporous filter membranes. There are many factors that affect the adsorption of ptfe sterilizing filter membranes, including the diameter, pore size, material, and type of filter media of the filter membrane. ionic strength, pH value, properties of the drug itself, etc.

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